Two months after a Uganda-wide mass vaccination campaign against yellow fever was launched in Lira city, the Lira Regional Referral Hospital is seeing enduring demand for the jab.

"Every day, we see about five to ten individuals coming in to request vaccination," says Peter Okello, the hospital's administrator.

The campaign, which kicked off in early June and targeted 13.3 million Ugandans aged nine months to 60 years of age, was a roaring success in Lira. Here, vaccination coverage exceeded 100%, with an impressive 12,000 vaccines administered, surpassing the initial target of 10,000 for the campaign week. "The demand was considerable, prompting us to request additional supplies," Okello explains.

Previously available on a paid basis through private health providers and deployed principally for travellers, the yellow fever vaccine this year became an integral part of the routine immunisation programme in Uganda, meaning it is now offered free-of-charge to every infant at age nine months.

According to the World Health Organization (WHO), the vaccine provides effective immunity within 10 days for 80–100% of recipients, and within 30 days for over 95% of recipients, and is protective for life after a single dose.

"Uganda is committed to controlling yellow fever transmission," Health Minister Dr Jane Ruth Aceng Ocero said in a statement. "Vaccines remain the main tool we have to efficiently prevent and contain yellow fever outbreaks."

Dr Daniel Kyabayinze, Director of Public Health at the Ministry of Health, says the goal of the yellow fever campaign and of the vaccine's introduction into the routine schedule is to eliminate yellow fever epidemics by 2026, which in turn is also the core goal of the global Eliminate Yellow Fever Epidemics (EYE) Strategy. "Introducing yellow fever into routine immunisation will ensure that all children under one year are protected against yellow fever," says Kyabayinze.

Sister Goretty Alinga, a senior assistant nursing officer at Lira Regional Referral Hospital and a vaccinator, was on the frontlines during the bustling campaign week in Lira.

"On the first day, I vaccinated 196 people, and on the campaign's final day, around 396 individuals received the jab from me,' she recounts. As a public health nurse, Alinga says she is an advocate of prevention over cure. She attests to heightened awareness of yellow fever in her community due to the vaccine campaign.

Pregnant women are not always excluded from yellow fever vaccine campaigns, but in this case they were. "We had to turn pregnant women away, but now after giving birth, they are coming to get the vaccine and bringing their children too," says Alinga.

“We had to turn pregnant women away, but now after giving birth, they are coming to get the vaccine and bringing their children too."

– Sister Goretty Alinga, nurse and vaccinator

The hospital offers yellow fever vaccines from Monday to Friday on a walk-in basis. "Men are usually impatient – when they decide to get vaccinated they don't like waiting," she says.

In the lead-up to the campaign, messages about the severity of the disease and significance of the vaccination drive were disseminated through various means. In Lira, messages were broadcast by community megaphones in markets and on streets, encouraging mobilising communities to converge on the designated dates.

Radio talk shows were conducted, conducting discussions on the vaccine's importance, with religious and political leaders weighing in in support of the vaccine via various channels. Notably, the campaign's launch was led by the Minister of Health, who is also the area's Member of Parliament and a native of the region.

Says Alinga, "The messages disseminated during the campaign truly raised awareness about the significance of vaccination and increased people's knowledge about yellow fever."

Uganda is considered a high-risk country for deadly, mosquito-transmitted yellow fever. Outbreaks are expected to occur every three to five years. In the year 2022 alone, the country witnessed two confirmed cases of yellow fever in Wakiso and Masaka districts.

But the recent vaccine push should change that threat profile. A 2021 research paper published in PLOS Medicine found that implementing vaccine campaigns was associated with an 86% reduction in the risk of yellow fever outbreaks in 34 African countries.

For Ugandans who missed the campaign window, the vaccine is now fortunately much nearer at hand. Speaking to a local radio station, Filbert Oketch, a Lira businessman, said: "Previously, it was expensive and cumbersome for individuals like me to go to Kampala for vaccination before travelling."

Despite the successes of the campaign in generating enthusiasm for the vaccine, it did reportedly prompt confusion for the most ancillary and bureaucratic of measures: a change in colour of the vaccination card. Expecting the traditional yellow, vaccination recipients were issued instead with a white card.

"The white card bears a government stamp, but people are used to getting a yellow card, not a white one. We have tried to explain that it is still valid, but they still complain," said Alinga.

Francis Ogwang, responsible for the Lira district cold chain, adds another layer to this concern. While it's possible for individuals who have received the vaccine to acquire a certificate online by entering their National ID information, this option poses challenges for many in the local community who lack access to the internet.

More importantly, though, Ogwang affirms that the cold room at the district retains sufficient doses to meet the ongoing demand. The available stock is slated to expire in 2024.

“If we vaccinate at least 80% of the population, we shall be able to eliminate yellow fever epidemics.”

– Dr Daniel Kyabayinze, Director of Public Health, Ministry of Health

In addition to public health facilities, the private sector is also allocated vaccines for administration to the public, free of charge. "They maintain records and share them with us for oversight," Ogwang explains.

Kyabayinze offers a hopeful picture of the future. "These campaigns are not a response to any outbreak, but they are to stop future outbreaks, and that's why they are termed preventive," he says. "If we vaccinate at least 80% of the population, we shall be able to eliminate yellow fever epidemics."

This article is republished from VaccinesWork under a Creative Commons license. Read the original article. VaccinesWork is an award-winning digital platform hosted by Gavi, the Vaccine Alliance covering news, features and explainers from every corner of global health and immunisation.